Cancer is a major human health problem and a completely effective therapy is not available for most types of cancer the expected benefit of the treatment is assessed in terms of a reduction in both the size of the tumor and dissemination of the cancer imaging is an ideal tool with which to evaluate response the aim of using imaging as a surrogate biomarker for therapeutic response in . In the therapy assessment setting multifunctional imaging can provide valuable information in a number of areas including a pretreatment prediction of tumor response b improved understanding of the biologic effects of therapy c predicting response early after initiating therapy d monitoring the effects of radiation and e understanding the mechanisms of action of novel drugs. Who tumor response criteria and more recently recist response evaluation criteria in solid tumors have provided means to objectively measure tumor response in clinical trials with imaging these guidelines have been rapidly adopted in clinical practice to monitor patient treatment and for therapy planning however relying only on anatomical information is not always sufficient when . In my opinion imaging tumor response to therapy is an excellent book for all the medical professionals involved in oncology the book is well priced and is an important addition to anyone who is interested in the oncology field reviewed by khalid khashoggi md article history published online jan 2014 published in print jan 2014 figures references related details recommended